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KMID : 0363220080460070993
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Korean Journal of Dermatology
2008 Volume.46 No. 7 p.993 ~ p.995
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A Case of Sclerodermatous Chronic Graft versus Host Disease Associated with Cicatricial Alopecia
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Cha Sang-Hee
Park Hyun-Jeong
Lee Jun-Young
Cho Baik-Kee
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Abstract
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Cutaneous chronic graft versus host disease (GVHD) has been classified into lichenoid and scleroderma-like forms. However, some atypical cutaneous manifestation may be prevalent. A 9-year-old boy was diagnosed with acute lymphoblastic leukemia in March 2004 and underwent unrelated matched bone marrow transplantation (uBMT) in February 2005. However, one month after transplantation, he started suffering from acute GVHD. After clinical recovery, extensive sclerotic patch or plaque with alopecia developed. The scalp biopsy showed atrophy of the epidermis, inflammatory cell infiltration and sclerosis in the dermis which were consistent with cicatricial alopecia. We report a case of sclerodermatous chronic cutaneous GVHD showing cicatricial alopecia.
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